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Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia

Innate immunity is a first line defense against Mycobacterium tuberculosis infection where inflammasome activation and secretion of the pro-inflammatory cytokine IL-1beta, plays a major role. Thus, genetic polymorphisms in innate immunity-related genes such as CARD8 and NLRP3 may contribute to the u...

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Detalles Bibliográficos
Autores principales:	Abate, Ebba, Blomgran, Robert, Verma, Deepti, Lerm, Maria, Fredrikson, Mats, Belayneh, Meseret, Söderkvist, Peter, Stendahl, Olle, Schön, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395648/ https://www.ncbi.nlm.nih.gov/pubmed/30816317 http://dx.doi.org/10.1038/s41598-019-40121-8

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