Atg7-dependent canonical autophagy regulates the degradation of aquaporin 2 in prolonged hypokalemia

Prolonged hypokalemia induces a decrease of urinary concentrating ability via down-regulation of aquaporin 2 (AQP2); however, the precise mechanisms remain unknown. To investigate the role of autophagy in the degradation of AQP2, we generated the principal cell-specific Atg7 deletion (Atg7(Δpc)) mic...

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Detalles Bibliográficos
Autores principales: Kim, Wan-Young, Nam, Sun Ah, Choi, Arum, Kim, Yu-Mi, Park, Sang Hee, Kim, Hong Lim, Kim, Hyang, Han, Ki-Hwan, Yang, Chul Woo, Lee, Myung-Shik, Kim, Yong Kyun, Kim, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395725/
https://www.ncbi.nlm.nih.gov/pubmed/30816234
http://dx.doi.org/10.1038/s41598-019-39702-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395725/
https://www.ncbi.nlm.nih.gov/pubmed/30816234
http://dx.doi.org/10.1038/s41598-019-39702-4

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