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Ovarian Hormone-dependent and Spinal ERK Activation-regulated Nociceptive Hypersensitivity in Female Rats with Acid Injection-induced Chronic Widespread Muscle Pain

Symptoms of chronic widespread muscle pain (CWP) meet most of the diagnostic criteria for fibromyalgia syndrome, which is prevalent in females. We used an acid injection-induced muscle pain (AIMP) model to mimic CWP. After female rats received an ovariectomy (OVX), acid saline solution was injected...

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Detalles Bibliográficos
Autores principales: Chang, Ju-Hsin, Tsai, Shih-Ying, Zeng, Yen-Jing, Liu, Yu-Cheng, Li, Chi-Yuan, Chen, Kuen-Bao, Wen, Yeong-Ray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395742/
https://www.ncbi.nlm.nih.gov/pubmed/30816240
http://dx.doi.org/10.1038/s41598-019-39472-z

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