Cdk1-mediated DIAPH1 phosphorylation maintains metaphase cortical tension and inactivates the spindle assembly checkpoint at anaphase

Animal cells undergo rapid rounding during mitosis, ensuring proper chromosome segregation, during which an outward rounding force abruptly increases upon prometaphase entry and is maintained at a constant level during metaphase. Initial cortical tension is generated by the actomyosin system to whic...

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Detalles Bibliográficos
Autores principales: Nishimura, Koutarou, Johmura, Yoshikazu, Deguchi, Katashi, Jiang, Zixian, Uchida, Kazuhiko S. K., Suzuki, Narumi, Shimada, Midori, Chiba, Yoshie, Hirota, Toru, Yoshimura, Shige H., Kono, Keiko, Nakanishi, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395754/
https://www.ncbi.nlm.nih.gov/pubmed/30816115
http://dx.doi.org/10.1038/s41467-019-08957-w

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