Complement-dependent outer membrane perturbation sensitizes Gram-negative bacteria to Gram-positive specific antibiotics

Gram-negative bacteria are refractory to the action of many antibiotics due to their impermeable outer membrane. An important player of the immune system is the complement system, a protein network in serum that directly kills Gram-negative bacteria through pore-formation by the Membrane Attack Comp...

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Detalles Bibliográficos
Autores principales: Heesterbeek, D. A. C., Martin, N. I., Velthuizen, A., Duijst, M., Ruyken, M., Wubbolts, R., Rooijakkers, S. H. M., Bardoel, B. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395757/
https://www.ncbi.nlm.nih.gov/pubmed/30816122
http://dx.doi.org/10.1038/s41598-019-38577-9

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