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Serum amyloid A binds to fibrin(ogen), promoting fibrin amyloid formation

Complex associations exist between inflammation and thrombosis, with the inflammatory state tending to promote coagulation. Fibrinogen, an acute phase protein, has been shown to interact with the amyloidogenic ß-amyloid protein of Alzheimer’s disease. However, little is known about the association b...

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Detalles Bibliográficos
Autores principales: Page, Martin J., Thomson, Greig J. A., Nunes, J. Massimo, Engelbrecht, Anna-Mart, Nell, Theo A, de Villiers, Willem J. S., de Beer, Maria C., Engelbrecht, Lize, Kell, Douglas B., Pretorius, Etheresia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395759/
https://www.ncbi.nlm.nih.gov/pubmed/30816210
http://dx.doi.org/10.1038/s41598-019-39056-x