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Regulation of Cathepsin E gene expression by the transcription factor Kaiso in MRL/lpr mice derived CD4+ T cells

Global DNA hypomethylation in CD4+ cells in systemic lupus erythematosus (SLE) was suggested to play a key role in the pathogenesis. To identify new methylation-sensitive genes, we integrated genome-wide DNA methylation and mRNA profiling data in CD4+ cells of MRL/lpr (MRL) and C57BL6/J (B6) mice. W...

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Detalles Bibliográficos
Autores principales:	Hiramatsu, Sumie, Watanabe, Katsue S, Zeggar, Sonia, Asano, Yosuke, Miyawaki, Yoshia, Yamamura, Yuriko, Katsuyama, Eri, Katsuyama, Takayuki, Watanabe, Haruki, Takano-Narazaki, Mariko, Matsumoto, Yoshinori, Kawabata, Tomoko, Sada, Ken-Ei, Wada, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395770/ https://www.ncbi.nlm.nih.gov/pubmed/30816218 http://dx.doi.org/10.1038/s41598-019-38809-y

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