Cav3.2 T-type calcium channels shape electrical firing in mouse Lamina II neurons

The T-type calcium channel, Cav3.2, is necessary for acute pain perception, as well as mechanical and cold allodynia in mice. Being found throughout sensory pathways, from excitatory primary afferent neurons up to pain matrix structures, it is a promising target for analgesics. In our study, Cav3.2...

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Detalles Bibliográficos
Autores principales: Candelas, Miriam, Reynders, Ana, Arango-Lievano, Margarita, Neumayer, Christoph, Fruquière, Antoine, Demes, Elsa, Hamid, Jawed, Lemmers, Céline, Bernat, Claire, Monteil, Arnaud, Compan, Vincent, Laffray, Sophie, Inquimbert, Perrine, Le Feuvre, Yves, Zamponi, Gerald W., Moqrich, Aziz, Bourinet, Emmanuel, Méry, Pierre-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395820/
https://www.ncbi.nlm.nih.gov/pubmed/30816223
http://dx.doi.org/10.1038/s41598-019-39703-3

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