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Honouring ‘Patient 38’ – a mother of all IVF mothers?

This commentary addresses one aspect of the early history of IVF in Britain. Specific data are re-examined from the recently published, anonymized database of medical records from the Oldham period of research conducted by Robert Edwards, Patrick Steptoe and their team of assistants between 1969 and...

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Detalles Bibliográficos
Autores principales: Littleton, Fiona, Bewley, Susan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395826/
https://www.ncbi.nlm.nih.gov/pubmed/30859140
http://dx.doi.org/10.1016/j.rbms.2018.10.009
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author Littleton, Fiona
Bewley, Susan
author_facet Littleton, Fiona
Bewley, Susan
author_sort Littleton, Fiona
collection PubMed
description This commentary addresses one aspect of the early history of IVF in Britain. Specific data are re-examined from the recently published, anonymized database of medical records from the Oldham period of research conducted by Robert Edwards, Patrick Steptoe and their team of assistants between 1969 and 1978. By focusing on a reformulation of the ‘scheduled treatment cycles per patient’, attention is drawn to the small, but nevertheless not insignificant, number of subjects who returned to Oldham at least five times or more to undergo innovative procedures and/or receive other experimental treatments over the duration of the research project. These multiple efforts are contrasted with the single or double treatment cycles received by the majority of the infertile women involved, including the only two experiencing live births, Lesley Brown and Grace Montgomery. The re-presented data facilitates new interpretations and raises fresh research questions about the nature of contemporary and present characterisations of the major protagonists in the ‘IVF story’, the identity of those women who originally took part and the origin of and reasons for discrepancies in the records maintained about research subjects.
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spelling pubmed-63958262019-03-11 Honouring ‘Patient 38’ – a mother of all IVF mothers? Littleton, Fiona Bewley, Susan Reprod Biomed Soc Online History This commentary addresses one aspect of the early history of IVF in Britain. Specific data are re-examined from the recently published, anonymized database of medical records from the Oldham period of research conducted by Robert Edwards, Patrick Steptoe and their team of assistants between 1969 and 1978. By focusing on a reformulation of the ‘scheduled treatment cycles per patient’, attention is drawn to the small, but nevertheless not insignificant, number of subjects who returned to Oldham at least five times or more to undergo innovative procedures and/or receive other experimental treatments over the duration of the research project. These multiple efforts are contrasted with the single or double treatment cycles received by the majority of the infertile women involved, including the only two experiencing live births, Lesley Brown and Grace Montgomery. The re-presented data facilitates new interpretations and raises fresh research questions about the nature of contemporary and present characterisations of the major protagonists in the ‘IVF story’, the identity of those women who originally took part and the origin of and reasons for discrepancies in the records maintained about research subjects. Elsevier 2018-11-09 /pmc/articles/PMC6395826/ /pubmed/30859140 http://dx.doi.org/10.1016/j.rbms.2018.10.009 Text en © 2018 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle History
Littleton, Fiona
Bewley, Susan
Honouring ‘Patient 38’ – a mother of all IVF mothers?
title Honouring ‘Patient 38’ – a mother of all IVF mothers?
title_full Honouring ‘Patient 38’ – a mother of all IVF mothers?
title_fullStr Honouring ‘Patient 38’ – a mother of all IVF mothers?
title_full_unstemmed Honouring ‘Patient 38’ – a mother of all IVF mothers?
title_short Honouring ‘Patient 38’ – a mother of all IVF mothers?
title_sort honouring ‘patient 38’ – a mother of all ivf mothers?
topic History
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395826/
https://www.ncbi.nlm.nih.gov/pubmed/30859140
http://dx.doi.org/10.1016/j.rbms.2018.10.009
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