Acetazolamide attenuates cardiac fibrosis induced by aortic constriction through inhibiting transforming growth factor-β1/Smad2 signaling pathway in mice

The effect and mechanism of acetazolamide on cardiac fibrosis induced by transverse aortic constriction (TAC) were investigated. C57BL/6 mice were subjected to TAC or sham operation and then were orally gavaged with acetazolamide (20 mg/kg/day). After 4 weeks of operation, cardiac function was detec...

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Detalles Bibliográficos
Autores principales: Huo, Qianqian, Wang, Ting, Wang, Tao, Zhang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395962/
https://www.ncbi.nlm.nih.gov/pubmed/30867716
http://dx.doi.org/10.3892/etm.2019.7210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6395962/
https://www.ncbi.nlm.nih.gov/pubmed/30867716
http://dx.doi.org/10.3892/etm.2019.7210

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