Histone deacetylase 2 is involved in DNA damage‐mediated cell death of human osteosarcoma cells through stimulation of the ATM/p53 pathway

Tumor suppressor p53 is a short‐lived nuclear transcription factor, which becomes stabilized and activated in response to a wide variety of cellular stresses. Around 50% of human cancer tissues carry p53 mutations, and certain p53 mutations contribute to chemoresistance. In the present study, we fou...

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Detalles Bibliográficos
Autores principales: Sun, Dan, Yu, Meng, Li, Yuanyuan, Xing, Haotian, Gao, Ying, Huang, Zhihong, Hao, Wenjun, Lu, Kaining, Kong, Chuize, Shimozato, Osamu, Ozaki, Toshinori, Zhu, Yuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396148/
https://www.ncbi.nlm.nih.gov/pubmed/30868056
http://dx.doi.org/10.1002/2211-5463.12585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396148/
https://www.ncbi.nlm.nih.gov/pubmed/30868056
http://dx.doi.org/10.1002/2211-5463.12585

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