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Histone deacetylase 2 is involved in DNA damage‐mediated cell death of human osteosarcoma cells through stimulation of the ATM/p53 pathway
Tumor suppressor p53 is a short‐lived nuclear transcription factor, which becomes stabilized and activated in response to a wide variety of cellular stresses. Around 50% of human cancer tissues carry p53 mutations, and certain p53 mutations contribute to chemoresistance. In the present study, we fou...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396148/ https://www.ncbi.nlm.nih.gov/pubmed/30868056 http://dx.doi.org/10.1002/2211-5463.12585 |