Addition of free poloxamer 407 to a new gene vector P407-PEI-K12 solution forms a sustained-release in situ hypergel that enhances cell transfection and extends gene expression

To address the concern around the efficiency/cytotoxicity ratio and the tumor-targeting effects of polyethylenimine (PEI), is a non-viral gene vector used for the delivery of the cancer therapy gene, poloxamer 407 (P407)-PEI-K12, was synthesized by cross-linking low-molecular weight PEI with P407 an...

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Detalles Bibliográficos
Autores principales: Shu, Hongmei, Zhang, Yaguang, Zhang, Min, Wu, Junwen, Cui, Mingxiao, Liu, Kehai, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396215/
https://www.ncbi.nlm.nih.gov/pubmed/30867738
http://dx.doi.org/10.3892/ol.2019.9944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396215/
https://www.ncbi.nlm.nih.gov/pubmed/30867738
http://dx.doi.org/10.3892/ol.2019.9944

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