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Early detection and prevention

The rapidly increasing incidence and mortality of cancer calls for a focused effort to increase the effect of cancer‐prevention efforts. In the area of early detection, there are major differences in the preventive impact of implemented screening policies, even when solid, evidence‐based internation...

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Detalles Bibliográficos
Autor principal: Dillner, Joakim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396346/
https://www.ncbi.nlm.nih.gov/pubmed/30676688
http://dx.doi.org/10.1002/1878-0261.12459
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author Dillner, Joakim
author_facet Dillner, Joakim
author_sort Dillner, Joakim
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description The rapidly increasing incidence and mortality of cancer calls for a focused effort to increase the effect of cancer‐prevention efforts. In the area of early detection, there are major differences in the preventive impact of implemented screening policies, even when solid, evidence‐based international recommendations are issued. Studies are needed to determine why evidence‐based interventions are not used and to investigate why effects are less than predicted by solid research on the subject. Currently, population‐based screening is recommended only for three forms of cancer (cervical, breast and colorectal cancer) but, given the increasing cancer burden, efforts are required to facilitate the discovery of new biomarkers for screening, as well as the identification of barriers to implementation of new cancer screening discoveries. The creation of a network of excellence in research on Cancer Prevention (Cancer Prevention Europe) is likely to significantly contribute to progress in these areas. In the present review, some possible strategies to ensure progress are discussed, with specific examples from the cervical cancer screening area.
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spelling pubmed-63963462019-03-11 Early detection and prevention Dillner, Joakim Mol Oncol Review Articles The rapidly increasing incidence and mortality of cancer calls for a focused effort to increase the effect of cancer‐prevention efforts. In the area of early detection, there are major differences in the preventive impact of implemented screening policies, even when solid, evidence‐based international recommendations are issued. Studies are needed to determine why evidence‐based interventions are not used and to investigate why effects are less than predicted by solid research on the subject. Currently, population‐based screening is recommended only for three forms of cancer (cervical, breast and colorectal cancer) but, given the increasing cancer burden, efforts are required to facilitate the discovery of new biomarkers for screening, as well as the identification of barriers to implementation of new cancer screening discoveries. The creation of a network of excellence in research on Cancer Prevention (Cancer Prevention Europe) is likely to significantly contribute to progress in these areas. In the present review, some possible strategies to ensure progress are discussed, with specific examples from the cervical cancer screening area. John Wiley and Sons Inc. 2019-02-27 2019-03 /pmc/articles/PMC6396346/ /pubmed/30676688 http://dx.doi.org/10.1002/1878-0261.12459 Text en © 2019 The Authors. Published by FEBS Press and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Dillner, Joakim
Early detection and prevention
title Early detection and prevention
title_full Early detection and prevention
title_fullStr Early detection and prevention
title_full_unstemmed Early detection and prevention
title_short Early detection and prevention
title_sort early detection and prevention
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396346/
https://www.ncbi.nlm.nih.gov/pubmed/30676688
http://dx.doi.org/10.1002/1878-0261.12459
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