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Early detection and therapeutics
Early detection, including cancer screening and surveillance, is emerging as one of the most important topics in modern oncology. Because symptomatic presentation remains the predominant route to cancer diagnosis, there is a growing interest in developing techniques to detect the disease at an early...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396365/ https://www.ncbi.nlm.nih.gov/pubmed/30677217 http://dx.doi.org/10.1002/1878-0261.12458 |
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author | Januszewicz, Wladyslaw Fitzgerald, Rebecca C. |
author_facet | Januszewicz, Wladyslaw Fitzgerald, Rebecca C. |
author_sort | Januszewicz, Wladyslaw |
collection | PubMed |
description | Early detection, including cancer screening and surveillance, is emerging as one of the most important topics in modern oncology. Because symptomatic presentation remains the predominant route to cancer diagnosis, there is a growing interest in developing techniques to detect the disease at an early, curative stage. Moreover, growing understanding of cancer biology has paved the way for prevention studies with the focus on therapeutic interventions for premalignant conditions. Where there is a recognisable precursor stage, such as a colorectal adenoma or Barrett's metaplasia, the removal of abnormal tissue prevents the development of cancer and enables stratification of the patient to a high‐risk group requiring further surveillance. Here, we provide a review of the available technologies for early diagnosis and minimally‐invasive treatment. |
format | Online Article Text |
id | pubmed-6396365 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-63963652019-03-11 Early detection and therapeutics Januszewicz, Wladyslaw Fitzgerald, Rebecca C. Mol Oncol Review Articles Early detection, including cancer screening and surveillance, is emerging as one of the most important topics in modern oncology. Because symptomatic presentation remains the predominant route to cancer diagnosis, there is a growing interest in developing techniques to detect the disease at an early, curative stage. Moreover, growing understanding of cancer biology has paved the way for prevention studies with the focus on therapeutic interventions for premalignant conditions. Where there is a recognisable precursor stage, such as a colorectal adenoma or Barrett's metaplasia, the removal of abnormal tissue prevents the development of cancer and enables stratification of the patient to a high‐risk group requiring further surveillance. Here, we provide a review of the available technologies for early diagnosis and minimally‐invasive treatment. John Wiley and Sons Inc. 2019-02-20 2019-03 /pmc/articles/PMC6396365/ /pubmed/30677217 http://dx.doi.org/10.1002/1878-0261.12458 Text en © 2019 The Authors. Published by FEBS Press and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Articles Januszewicz, Wladyslaw Fitzgerald, Rebecca C. Early detection and therapeutics |
title | Early detection and therapeutics |
title_full | Early detection and therapeutics |
title_fullStr | Early detection and therapeutics |
title_full_unstemmed | Early detection and therapeutics |
title_short | Early detection and therapeutics |
title_sort | early detection and therapeutics |
topic | Review Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396365/ https://www.ncbi.nlm.nih.gov/pubmed/30677217 http://dx.doi.org/10.1002/1878-0261.12458 |
work_keys_str_mv | AT januszewiczwladyslaw earlydetectionandtherapeutics AT fitzgeraldrebeccac earlydetectionandtherapeutics |