The herpesviral antagonist m152 reveals differential activation of STING‐dependent IRF and NF‐κB signaling and STING's dual role during MCMV infection

Cytomegaloviruses (CMVs) are master manipulators of the host immune response. Here, we reveal that the murine CMV (MCMV) protein m152 specifically targets the type I interferon (IFN) response by binding to stimulator of interferon genes (STING), thereby delaying its trafficking to the Golgi compartm...

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Detalles Bibliográficos
Autores principales: Stempel, Markus, Chan, Baca, Juranić Lisnić, Vanda, Krmpotić, Astrid, Hartung, Josephine, Paludan, Søren R, Füllbrunn, Nadia, Lemmermann, Niels AW, Brinkmann, Melanie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396373/
https://www.ncbi.nlm.nih.gov/pubmed/30696688
http://dx.doi.org/10.15252/embj.2018100983

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