Mapping global and local coevolution across 600 species to identify novel homologous recombination repair genes

The homologous recombination repair (HRR) pathway repairs DNA double-strand breaks in an error-free manner. Mutations in HRR genes can result in increased mutation rate and genomic rearrangements, and are associated with numerous genetic disorders and cancer. Despite intensive research, the HRR path...

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Detalles Bibliográficos
Autores principales: Sherill-Rofe, Dana, Rahat, Dolev, Findlay, Steven, Mellul, Anna, Guberman, Irene, Braun, Maya, Bloch, Idit, Lalezari, Alon, Samiei, Arash, Sadreyev, Ruslan, Goldberg, Michal, Orthwein, Alexandre, Zick, Aviad, Tabach, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396423/
https://www.ncbi.nlm.nih.gov/pubmed/30718334
http://dx.doi.org/10.1101/gr.241414.118

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