High-throughput functional analysis of lncRNA core promoters elucidates rules governing tissue specificity

Transcription initiates at both coding and noncoding genomic elements, including mRNA and long noncoding RNA (lncRNA) core promoters and enhancer RNAs (eRNAs). However, each class has a different expression profile with lncRNAs and eRNAs being the most tissue specific. How these complex differences...

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Detalles Bibliográficos
Autores principales: Mattioli, Kaia, Volders, Pieter-Jan, Gerhardinger, Chiara, Lee, James C., Maass, Philipp G., Melé, Marta, Rinn, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396428/
https://www.ncbi.nlm.nih.gov/pubmed/30683753
http://dx.doi.org/10.1101/gr.242222.118

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