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NFKB1 and MANBA Confer Disease Susceptibility to Primary Biliary Cholangitis via Independent Putative Primary Functional Variants

BACKGROUND & AIMS: Primary biliary cholangitis (PBC) is a chronic and cholestatic liver disease that eventually leads to cirrhosis and hepatic failure. We recently identified several susceptibility genes included NFKB1 and MANBA for PBC in the Japanese population by genome-wide association study...

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Detalles Bibliográficos
Autores principales: Hitomi, Yuki, Nakatani, Ken, Kojima, Kaname, Nishida, Nao, Kawai, Yosuke, Kawashima, Minae, Aiba, Yoshihiro, Nagasaki, Masao, Nakamura, Minoru, Tokunaga, Katsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396435/
https://www.ncbi.nlm.nih.gov/pubmed/30528300
http://dx.doi.org/10.1016/j.jcmgh.2018.11.006