A signalling cascade involving receptor-activated phospholipase A(2), glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility

BACKGROUND: Shp1, a tyrosine-phosphatase-1 containing the Src-homology 2 (SH2) domain, is involved in inflammatory and immune reactions, where it regulates diverse signalling pathways, usually by limiting cell responses through dephosphorylation of target molecules. Moreover, Shp1 regulates actin dy...

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Detalles Bibliográficos
Autores principales: Varone, Alessia, Mariggiò, Stefania, Patheja, Manpreet, Maione, Vincenzo, Varriale, Antonio, Vessichelli, Mariangela, Spano, Daniela, Formiggini, Fabio, Lo Monte, Matteo, Brancati, Nadia, Frucci, Maria, Del Vecchio, Pompea, D’Auria, Sabato, Flagiello, Angela, Iannuzzi, Clara, Luini, Alberto, Pucci, Piero, Banci, Lucia, Valente, Carmen, Corda, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396489/
https://www.ncbi.nlm.nih.gov/pubmed/30823936
http://dx.doi.org/10.1186/s12964-019-0329-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396489/
https://www.ncbi.nlm.nih.gov/pubmed/30823936
http://dx.doi.org/10.1186/s12964-019-0329-3

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