Cargando…

Nanoscale Ion Emitters in Native Mass Spectrometry for Measuring Ligand–Protein Binding Affinities

[Image: see text] Electrospray ionization (ESI) mass spectrometry (MS) is a crucial method for rapidly determining the interactions between small molecules and proteins with ultrahigh sensitivity. However, nonvolatile molecules and salts that are often necessary to stabilize the native structures of...

Descripción completa

Detalles Bibliográficos
Autores principales: Nguyen, Giang T. H., Tran, Thinh N., Podgorski, Matthew N., Bell, Stephen G., Supuran, Claudiu T., Donald, William A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396573/
https://www.ncbi.nlm.nih.gov/pubmed/30834319
http://dx.doi.org/10.1021/acscentsci.8b00787