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Mucosal-Associated Invariant T Cell Levels Are Reduced in the Peripheral Blood and Lungs of Children With Active Pulmonary Tuberculosis

Mucosal associated invariant T (MAIT) cells are unconventional, semi-invariant T lymphocytes that recognize microbial-derived vitamin B2 (riboflavin) biosynthesis precursor derivatives presented by the monomorphic MHC class 1-related (MR1) molecule. Upon microbial infection, MAIT cells rapidly produ...

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Detalles Bibliográficos
Autores principales:	Malka-Ruimy, Clara, Ben Youssef, Ghada, Lambert, Marion, Tourret, Marie, Ghazarian, Liana, Faye, Albert, Caillat-Zucman, Sophie, Houdouin, Véronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396712/ https://www.ncbi.nlm.nih.gov/pubmed/30853958 http://dx.doi.org/10.3389/fimmu.2019.00206

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