Cargando…
Protein Flexibility and Stiffness Enable Efficient Enzymatic Catalysis
[Image: see text] The enormous rate accelerations observed for many enzyme catalysts are due to strong stabilizing interactions between the protein and reaction transition state. The defining property of these catalysts is their specificity for binding the transition state with a much higher affinit...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2019
|
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6396832/ https://www.ncbi.nlm.nih.gov/pubmed/30703322 http://dx.doi.org/10.1021/jacs.8b10836 |