Palladium based nanoparticles for the treatment of advanced melanoma

IGF1R and CD44 are overexpressed in most advanced melanomas so we designed chemotherapeutic nanoparticles to target those receptors. Tris(dibenzylideneacetone)dipalladium (Tris DBA-Pd) is a novel inhibitor of N-myristoyltransferase 1 (NMT-1) and has proven in vivo activity against melanoma. However,...

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Detalles Bibliográficos
Autores principales: Elsey, Justin, Bubley, Jeffrey A., Zhu, Lei, Rao, Shikha, Sasaki, Maiko, Pollack, Brian P., Yang, Lily, Arbiser, Jack L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397149/
https://www.ncbi.nlm.nih.gov/pubmed/30824801
http://dx.doi.org/10.1038/s41598-019-40258-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397149/
https://www.ncbi.nlm.nih.gov/pubmed/30824801
http://dx.doi.org/10.1038/s41598-019-40258-6

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