Long term safety of targeted internalization of cell penetrating peptide crotamine into renal proximal tubular epithelial cells in vivo

Activated proximal tubular epithelial cells (PTECs) play a crucial role in progressive tubulo-interstitial fibrosis in native and transplanted kidneys. Targeting PTECs by non-viral delivery vectors might be useful to influence the expression of important genes and/or proteins in order to slow down r...

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Detalles Bibliográficos
Autores principales: Campeiro, Joana Darc, Dam, Wendy, Monte, Gabriela Guilherme, Porta, Lucas Carvalho, Oliveira, Lilian Caroline Gonçalves de, Nering, Marcela Bego, Viana, Gustavo Monteiro, Carapeto, Fernando Cintra, Oliveira, Eduardo Brandt, van den Born, Jacob, Hayashi, Mirian A. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397221/
https://www.ncbi.nlm.nih.gov/pubmed/30824773
http://dx.doi.org/10.1038/s41598-019-39842-7

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