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Metabolic effects of leptin receptor knockdown or reconstitution in adipose tissues
The relative contribution of peripheral and central leptin signalling to the regulation of metabolism and the mechanisms through which leptin affects glucose homeostasis have not been fully elucidated. We generated complementary lines of mice with either leptin receptor (Lepr) knockdown or reconstit...
Autores principales: | Pereira, Sandra, O’Dwyer, Shannon M., Webber, Travis D., Baker, Robert K., So, Victor, Ellis, Cara E., Yoon, Ji Soo, Mojibian, Majid, Glavas, Maria M., Karunakaran, Subashini, Clee, Susanne M., Covey, Scott D., Kieffer, Timothy J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397253/ https://www.ncbi.nlm.nih.gov/pubmed/30824713 http://dx.doi.org/10.1038/s41598-019-39498-3 |
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