Limited available evidence supports theoretical predictions of reduced vaccine efficacy at higher exposure dose

Understanding the causes of vaccine failure is important for predicting disease dynamics in vaccinated populations and planning disease interventions. Pathogen exposure dose and heterogeneity in host susceptibility have both been implicated as important factors that may reduce overall vaccine effica...

Descripción completa

Detalles Bibliográficos
Autores principales: Langwig, Kate E., Gomes, M. Gabriela M., Clark, Mercedes D., Kwitny, Molly, Yamada, Steffany, Wargo, Andrew R., Lipsitch, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397254/
https://www.ncbi.nlm.nih.gov/pubmed/30824732
http://dx.doi.org/10.1038/s41598-019-39698-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397254/
https://www.ncbi.nlm.nih.gov/pubmed/30824732
http://dx.doi.org/10.1038/s41598-019-39698-x

Ejemplares similares