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Limited available evidence supports theoretical predictions of reduced vaccine efficacy at higher exposure dose
Understanding the causes of vaccine failure is important for predicting disease dynamics in vaccinated populations and planning disease interventions. Pathogen exposure dose and heterogeneity in host susceptibility have both been implicated as important factors that may reduce overall vaccine effica...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397254/ https://www.ncbi.nlm.nih.gov/pubmed/30824732 http://dx.doi.org/10.1038/s41598-019-39698-x |