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Mechanisms of Osteoblastic Bone Metastasis in Prostate Cancer: Role of Prostatic Acid Phosphatase

Prostate cancer (PCa) preferentially metastasizes to bone, leading to complications including severe pain, fractures, spinal cord compression, bone marrow suppression, and a mortality of ∼70%. In spite of recent advances in chemo-, hormonal, and radiation therapies, bone-metastatic, castrate-resista...

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Detalles Bibliográficos
Autores principales: Quiroz-Munoz, Mariana, Izadmehr, Sudeh, Arumugam, Dushyanthy, Wong, Beatrice, Kirschenbaum, Alexander, Levine, Alice C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397422/
https://www.ncbi.nlm.nih.gov/pubmed/30842989
http://dx.doi.org/10.1210/js.2018-00425