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Molecular tumor analysis and liquid biopsy: a feasibility investigation analyzing circulating tumor DNA in patients with central nervous system lymphomas

BACKGROUND: Central nervous system lymphomas (CNSL) is a devastating disease. Currently, a confirmatory biopsy is required prior to treatment. OBJECTIVE: Our investigation aims to prove the feasibility of a minimally-invasive diagnostic approach for the molecular characterization of CNSL. METHODS: T...

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Detalles Bibliográficos
Autores principales: Hickmann, Anne-Katrin, Frick, Maximilian, Hadaschik, Dirk, Battke, Florian, Bittl, Markus, Ganslandt, Oliver, Biskup, Saskia, Döcker, Dennis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397454/
https://www.ncbi.nlm.nih.gov/pubmed/30823914
http://dx.doi.org/10.1186/s12885-019-5394-x