Structural basis for HOCl recognition and regulation mechanisms of HypT, a hypochlorite-specific transcriptional regulator

Hypochlorous acid (HOCl) is generated in the immune system to kill microorganisms. In Escherichia coli, a hypochlorite-specific transcription regulator, HypT, has been characterized. HypT belongs to the LysR-type transcriptional regulator (LTTR) family that contains a DNA-binding domain (DBD) and a...

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Detalles Bibliográficos
Autores principales: Jo, Inseong, Kim, Dajeong, No, Taehoon, Hong, Seokho, Ahn, Jinsook, Ryu, Sangryeol, Ha, Nam-Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397515/
https://www.ncbi.nlm.nih.gov/pubmed/30733296
http://dx.doi.org/10.1073/pnas.1811509116

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