Cryo-EM structure and in vitro DNA packaging of a thermophilic virus with supersized T=7 capsids

Double-stranded DNA viruses, including bacteriophages and herpesviruses, package their genomes into preformed capsids, using ATP-driven motors. Seeking to advance structural and mechanistic understanding, we established in vitro packaging for a thermostable bacteriophage, P23-45 of Thermus thermophi...

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Detalles Bibliográficos
Autores principales: Bayfield, Oliver W., Klimuk, Evgeny, Winkler, Dennis C., Hesketh, Emma L., Chechik, Maria, Cheng, Naiqian, Dykeman, Eric C., Minakhin, Leonid, Ranson, Neil A., Severinov, Konstantin, Steven, Alasdair C., Antson, Alfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397560/
https://www.ncbi.nlm.nih.gov/pubmed/30737287
http://dx.doi.org/10.1073/pnas.1813204116

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