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Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration

Midbrain dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in controlling cognitive processes, reward mechanisms, and motor functions. The hormonal actions of insulin-like growth factor 1 (IGF-1) produced by the liver have been well described, but the ro...

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Detalles Bibliográficos
Autores principales: Pristerà, Alessandro, Blomeley, Craig, Lopes, Emanuel, Threlfell, Sarah, Merlini, Elisa, Burdakov, Denis, Cragg, Stephanie, Guillemot, François, Ang, Siew-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397563/
https://www.ncbi.nlm.nih.gov/pubmed/30808767
http://dx.doi.org/10.1073/pnas.1806820116