Cargando…
Dopamine neuron-derived IGF-1 controls dopamine neuron firing, skill learning, and exploration
Midbrain dopamine neurons, which can be regulated by neuropeptides and hormones, play a fundamental role in controlling cognitive processes, reward mechanisms, and motor functions. The hormonal actions of insulin-like growth factor 1 (IGF-1) produced by the liver have been well described, but the ro...
Autores principales: | Pristerà, Alessandro, Blomeley, Craig, Lopes, Emanuel, Threlfell, Sarah, Merlini, Elisa, Burdakov, Denis, Cragg, Stephanie, Guillemot, François, Ang, Siew-Lan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397563/ https://www.ncbi.nlm.nih.gov/pubmed/30808767 http://dx.doi.org/10.1073/pnas.1806820116 |
Ejemplares similares
-
Genetic deletion of vesicular glutamate transporter in dopamine neurons increases vulnerability to MPTP-induced neurotoxicity in mice
por: Shen, Hui, et al.
Publicado: (2018) -
A transient dopamine signal encodes subjective value and causally influences demand in an economic context
por: Schelp, Scott A., et al.
Publicado: (2017) -
Dorsal striatal dopamine D1 receptor availability predicts an instrumental bias in action learning
por: de Boer, Lieke, et al.
Publicado: (2019) -
Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease
por: Dunn, Amy R., et al.
Publicado: (2017) -
Dopamine D2 receptor-mediated circuit from the central amygdala to the bed nucleus of the stria terminalis regulates impulsive behavior
por: Kim, Bokyeong, et al.
Publicado: (2018)