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Histone Modification Marks Strongly Regulate CDH1 Promoter in Prostospheres as A Model of Prostate Cancer Stem Like Cells

OBJECTIVE: Cadherin-1 (CDH1) plays an important role in the metastasis, while expression of this protein is under control of epigenetic changes on its gene promoter. Therefore we evaluated both DNA methylation (DNAmet) and histone modification marks of CDH1 in prostate cancer stem like cells (PCSLCs...

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Detalles Bibliográficos
Autores principales:	Shokraii, Fatemeh, Moharrami, Maryam, Motamed, Nasrin, Shahhoseini, Maryam, Totonchi, Mehdi, Ezzatizadeh, Vahid, Firouzi, Javad, Khosravani, Pardis, Ebrahimi, Marzieh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royan Institute 2019
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397603/ https://www.ncbi.nlm.nih.gov/pubmed/30825285 http://dx.doi.org/10.22074/cellj.2019.5702

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