TRPV1 protects renal ischemia-reperfusion injury in diet-induced obese mice by enhancing CGRP release and increasing renal blood flow

BACKGROUND: Obesity is a major risk factor for end-stage renal disease. Using transient receptor potential vanilloid 1 knockout (TRPV1(−/−)) mice, we tested the hypothesis that TRPV1 protects against obesity-induced exacerbation of renal ischemia-reperfusion (I/R) injury. METHODS: TRPV1(−/−) and wil...

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Detalles Bibliográficos
Autores principales: Zhong, Beihua, Ma, Shuangtao, Wang, Donna H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Anatomy and Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397633/
https://www.ncbi.nlm.nih.gov/pubmed/30834186
http://dx.doi.org/10.7717/peerj.6505

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397633/
https://www.ncbi.nlm.nih.gov/pubmed/30834186
http://dx.doi.org/10.7717/peerj.6505

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