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A deletion in the Ctns gene causes renal tubular dysfunction and cystine accumulation in LEA/Tohm rats
The Long-Evans Agouti (LEA/Tohm) rat has recently been established as a new rat model of type 2 diabetes. The onset of diabetes mellitus was observed only in male LEA/Tohm rats; however, urinary glucose appeared before the onset of diabetes. To clarify the genetic basis of urinary glucose, we perfor...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397714/ https://www.ncbi.nlm.nih.gov/pubmed/30591971 http://dx.doi.org/10.1007/s00335-018-9790-3 |