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Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy

BACKGROUND: Single loop reconstruction (SLR) was routine in our institution for patients undergoing pancreatico-duodenectomy (PD). Roux-en Y reconstruction with an isolated gastric limb (RIGL) recently became the reconstruction of choice. AIM: To evaluate the impact of RIGL on incidence and severity...

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Autores principales: Ben-Ishay, Offir, Zhaya, Reem Abu, Kluger, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397796/
https://www.ncbi.nlm.nih.gov/pubmed/30842815
http://dx.doi.org/10.4240/wjgs.v11.i2.93
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author Ben-Ishay, Offir
Zhaya, Reem Abu
Kluger, Yoram
author_facet Ben-Ishay, Offir
Zhaya, Reem Abu
Kluger, Yoram
author_sort Ben-Ishay, Offir
collection PubMed
description BACKGROUND: Single loop reconstruction (SLR) was routine in our institution for patients undergoing pancreatico-duodenectomy (PD). Roux-en Y reconstruction with an isolated gastric limb (RIGL) recently became the reconstruction of choice. AIM: To evaluate the impact of RIGL on incidence and severity of delayed gastric emptying (DGE). METHODS: This is a single institution, retrospective analysis of patients undergoing PD. All patients undergoing PD from July 2010 through December 2016 were included in the study. Outcome of RIGL were compared to SLR. Primary measure of outcome included incidence and severity of DGE. Secondary measures of outcome were overall complications and postoperative mortality. RESULTS: One hundred and seventy-nine patients were included in the study. Fifty-two had RIGL, 127 had SLR. Overall complication rate was 40.2%, patients in the RIGL group experienced lower rates of DGE (15.4% vs 59.1%, P = 0.001). Other patient related outcomes were also significantly reduced: day of nasogastric tube removal (3 vs 5, P < 0.001), regain of normal diet (8 vs 9, P < 0.001). On multivariate analysis RIGL was associated independently with reduced rates of DGE (P < 0.001, OR 0.14) CONCLUSION: The current study shows that RIGL reduces the rate of DGE after PD. Further prospective randomized controlled trials are required to affirm the current data.
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spelling pubmed-63977962019-03-06 Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy Ben-Ishay, Offir Zhaya, Reem Abu Kluger, Yoram World J Gastrointest Surg Case Control Study BACKGROUND: Single loop reconstruction (SLR) was routine in our institution for patients undergoing pancreatico-duodenectomy (PD). Roux-en Y reconstruction with an isolated gastric limb (RIGL) recently became the reconstruction of choice. AIM: To evaluate the impact of RIGL on incidence and severity of delayed gastric emptying (DGE). METHODS: This is a single institution, retrospective analysis of patients undergoing PD. All patients undergoing PD from July 2010 through December 2016 were included in the study. Outcome of RIGL were compared to SLR. Primary measure of outcome included incidence and severity of DGE. Secondary measures of outcome were overall complications and postoperative mortality. RESULTS: One hundred and seventy-nine patients were included in the study. Fifty-two had RIGL, 127 had SLR. Overall complication rate was 40.2%, patients in the RIGL group experienced lower rates of DGE (15.4% vs 59.1%, P = 0.001). Other patient related outcomes were also significantly reduced: day of nasogastric tube removal (3 vs 5, P < 0.001), regain of normal diet (8 vs 9, P < 0.001). On multivariate analysis RIGL was associated independently with reduced rates of DGE (P < 0.001, OR 0.14) CONCLUSION: The current study shows that RIGL reduces the rate of DGE after PD. Further prospective randomized controlled trials are required to affirm the current data. Baishideng Publishing Group Inc 2019-02-27 2019-02-27 /pmc/articles/PMC6397796/ /pubmed/30842815 http://dx.doi.org/10.4240/wjgs.v11.i2.93 Text en ©The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Case Control Study
Ben-Ishay, Offir
Zhaya, Reem Abu
Kluger, Yoram
Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy
title Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy
title_full Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy
title_fullStr Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy
title_full_unstemmed Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy
title_short Dual loop (Roux en Y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy
title_sort dual loop (roux en y) reconstruction with isolated gastric limb reduces delayed gastric emptying after pancreatico-duodenectomy
topic Case Control Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397796/
https://www.ncbi.nlm.nih.gov/pubmed/30842815
http://dx.doi.org/10.4240/wjgs.v11.i2.93
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