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Bicuculline Reduces Neuroinflammation in Hippocampus and Improves Spatial Learning and Anxiety in Hyperammonemic Rats. Role of Glutamate Receptors

Patients with liver cirrhosis may develop minimal hepatic encephalopathy (MHE) with mild cognitive impairment. Hyperammonemia is a main contributor to cognitive impairment in MHE, which is mediated by neuroinflammation. GABAergic neurotransmission is altered in hyperammonemic rats. We hypothesized t...

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Detalles Bibliográficos
Autores principales:	Malaguarnera, Michele, Llansola, Marta, Balzano, Tiziano, Gómez-Giménez, Belén, Antúnez-Muñoz, Carles, Martínez-Alarcón, Núria, Mahdinia, Rahebeh, Felipo, Vicente
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397886/ https://www.ncbi.nlm.nih.gov/pubmed/30858801 http://dx.doi.org/10.3389/fphar.2019.00132

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