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Scutellarin suppresses proliferation and promotes apoptosis in A549 lung adenocarcinoma cells via AKT/mTOR/4EBP1 and STAT3 pathways

BACKGROUND: Scutellarin (SCU), a flavonoid isolated from Erigeron breviscapus (Vant.) Hand.‐Mazz., increases autophagy and apoptosis in the adenocarcinoma A549 cell line, which is resistant to cisplatin. However, whether SCU alone has antitumor activity against non‐small cell lung cancer (NSCLC) is...

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Detalles Bibliográficos
Autores principales:	Cao, Pikun, Liu, Bin, Du, Feng, Li, Dong, Wang, Yongzheng, Yan, Xiaoyan, Li, Xiao, Li, Yuliang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons Australia, Ltd 2019
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397905/ https://www.ncbi.nlm.nih.gov/pubmed/30666790 http://dx.doi.org/10.1111/1759-7714.12962

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