A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant

A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, who achieved completed morphological remission, and FLT3-itd negativity, following 9 cycles of azacitadine in combination with escalating doses of donor lymphocyte infusions following relapse 18 months...

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Autores principales: Horgan, Claire, Kanellopoulos, Alexandros, Paneesha, Shankara, Kishore, Bhuvan, Lovell, Richard, Nikolousis, Emmanouil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397996/
https://www.ncbi.nlm.nih.gov/pubmed/30915202
http://dx.doi.org/10.4081/hr.2019.7800
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author Horgan, Claire
Kanellopoulos, Alexandros
Paneesha, Shankara
Kishore, Bhuvan
Lovell, Richard
Nikolousis, Emmanouil
author_facet Horgan, Claire
Kanellopoulos, Alexandros
Paneesha, Shankara
Kishore, Bhuvan
Lovell, Richard
Nikolousis, Emmanouil
author_sort Horgan, Claire
collection PubMed
description A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, who achieved completed morphological remission, and FLT3-itd negativity, following 9 cycles of azacitadine in combination with escalating doses of donor lymphocyte infusions following relapse 18 months post reduced intensity HLAA mismatch Campath conditioning allogeneic stem cell transplant.
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spelling pubmed-63979962019-03-26 A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant Horgan, Claire Kanellopoulos, Alexandros Paneesha, Shankara Kishore, Bhuvan Lovell, Richard Nikolousis, Emmanouil Hematol Rep Case Report A unique case of primary refractory FLT3-itd mutated acute myeloid leukemia in an elderly patient, who achieved completed morphological remission, and FLT3-itd negativity, following 9 cycles of azacitadine in combination with escalating doses of donor lymphocyte infusions following relapse 18 months post reduced intensity HLAA mismatch Campath conditioning allogeneic stem cell transplant. PAGEPress Publications, Pavia, Italy 2019-02-25 /pmc/articles/PMC6397996/ /pubmed/30915202 http://dx.doi.org/10.4081/hr.2019.7800 Text en ©Copyright C. Horgan et al., 2019 http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Horgan, Claire
Kanellopoulos, Alexandros
Paneesha, Shankara
Kishore, Bhuvan
Lovell, Richard
Nikolousis, Emmanouil
A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant
title A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant
title_full A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant
title_fullStr A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant
title_full_unstemmed A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant
title_short A unique case of durable complete remission after salvage with azacitidine and DLI for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant
title_sort unique case of durable complete remission after salvage with azacitidine and dli for high risk flt-3 positive acute myeloid leukemia, following relapse 18 months post allogeneic stem cell transplant
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397996/
https://www.ncbi.nlm.nih.gov/pubmed/30915202
http://dx.doi.org/10.4081/hr.2019.7800
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