Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR

Long-term exposure to high glucose induces vascular endothelial inflammation that can result in cardiovascular disease. Astragaloside IV (As-IV) is widely used for anti-inflammatory treatment of cardiovascular diseases. However, its mechanism of action is still not fully understood. In this study, w...

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Detalles Bibliográficos
Autores principales: Leng, Bin, Zhang, Yingjie, Liu, Xinran, Zhang, Zhen, Liu, Yang, Wang, Hongxin, Lu, Meili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398021/
https://www.ncbi.nlm.nih.gov/pubmed/30906223
http://dx.doi.org/10.1155/2019/1082497

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