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Dietary intervention for canine epilepsy: Two case reports

Epilepsy is a common neurologic disorder in humans and domesticated canines. In both species the etiology is diverse and complex, and even with medication a significant portion of the population does not experience sufficient seizure control and/or has unacceptable side effects. Humans often try alt...

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Autores principales: Masino, Susan A., Freedgood, Natalie R., Reichert, Hannah R., Director, Chris J., Whittemore, Vicky H., Zupec‐Kania, Beth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398089/
https://www.ncbi.nlm.nih.gov/pubmed/30868131
http://dx.doi.org/10.1002/epi4.12305
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author Masino, Susan A.
Freedgood, Natalie R.
Reichert, Hannah R.
Director, Chris J.
Whittemore, Vicky H.
Zupec‐Kania, Beth
author_facet Masino, Susan A.
Freedgood, Natalie R.
Reichert, Hannah R.
Director, Chris J.
Whittemore, Vicky H.
Zupec‐Kania, Beth
author_sort Masino, Susan A.
collection PubMed
description Epilepsy is a common neurologic disorder in humans and domesticated canines. In both species the etiology is diverse and complex, and even with medication a significant portion of the population does not experience sufficient seizure control and/or has unacceptable side effects. Humans often try alternatives such as dietary therapy or brain surgery, but in dogs, brain surgery is rarely an option and, despite potential benefits, there are no standard recommendations for a dietary approach. Herein we describe 2 retrospective case studies detailing the effects of homemade diets prepared for dogs with uncontrolled epileptic seizures and/or toxic side effects of medication. Basic recipes are provided for each formula—a high‐fat “ketogenic” diet and a partial “whole food” diet. Carbohydrate content was reduced or controlled, and in one case this was proven to be essential for seizure control: ingesting carbohydrates would reverse the benefits of the diet and precipitate a seizure. Both dogs experienced fewer seizures and side effects when eating these modified diets compared to when they were administered antiepileptic drugs, including complete cessation of seizures for extended periods. Practical advantages and success of these homemade dietary interventions highlight the potential for diet‐based metabolic therapy as a treatment option for seizures not only in humans but also in dogs.
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spelling pubmed-63980892019-03-13 Dietary intervention for canine epilepsy: Two case reports Masino, Susan A. Freedgood, Natalie R. Reichert, Hannah R. Director, Chris J. Whittemore, Vicky H. Zupec‐Kania, Beth Epilepsia Open Short Research Article Epilepsy is a common neurologic disorder in humans and domesticated canines. In both species the etiology is diverse and complex, and even with medication a significant portion of the population does not experience sufficient seizure control and/or has unacceptable side effects. Humans often try alternatives such as dietary therapy or brain surgery, but in dogs, brain surgery is rarely an option and, despite potential benefits, there are no standard recommendations for a dietary approach. Herein we describe 2 retrospective case studies detailing the effects of homemade diets prepared for dogs with uncontrolled epileptic seizures and/or toxic side effects of medication. Basic recipes are provided for each formula—a high‐fat “ketogenic” diet and a partial “whole food” diet. Carbohydrate content was reduced or controlled, and in one case this was proven to be essential for seizure control: ingesting carbohydrates would reverse the benefits of the diet and precipitate a seizure. Both dogs experienced fewer seizures and side effects when eating these modified diets compared to when they were administered antiepileptic drugs, including complete cessation of seizures for extended periods. Practical advantages and success of these homemade dietary interventions highlight the potential for diet‐based metabolic therapy as a treatment option for seizures not only in humans but also in dogs. John Wiley and Sons Inc. 2019-02-14 /pmc/articles/PMC6398089/ /pubmed/30868131 http://dx.doi.org/10.1002/epi4.12305 Text en © 2019 The Authors. Epilepsia Open published by Wiley Periodicals Inc. on behalf of International League Against Epilepsy. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Short Research Article
Masino, Susan A.
Freedgood, Natalie R.
Reichert, Hannah R.
Director, Chris J.
Whittemore, Vicky H.
Zupec‐Kania, Beth
Dietary intervention for canine epilepsy: Two case reports
title Dietary intervention for canine epilepsy: Two case reports
title_full Dietary intervention for canine epilepsy: Two case reports
title_fullStr Dietary intervention for canine epilepsy: Two case reports
title_full_unstemmed Dietary intervention for canine epilepsy: Two case reports
title_short Dietary intervention for canine epilepsy: Two case reports
title_sort dietary intervention for canine epilepsy: two case reports
topic Short Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398089/
https://www.ncbi.nlm.nih.gov/pubmed/30868131
http://dx.doi.org/10.1002/epi4.12305
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