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C57BL/6J and C57BL/6N substrains differentially influence phenotype severity in the Scn1a (+/−) mouse model of Dravet syndrome
Many disease‐relevant phenotypes modeled in inbred mice have been shown to be strain‐dependent, indicating the important influence of genetic background on disease phenotypes. Although C57BL/6 mice are one of the most commonly used inbred strains in laboratory research, there are multiple substrains...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398090/ https://www.ncbi.nlm.nih.gov/pubmed/30868126 http://dx.doi.org/10.1002/epi4.12287 |