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Spatiotemporal expression and inhibition of prolyl oligopeptidase contradict its involvement in key pathologic mechanisms of kainic acid–induced temporal lobe epilepsy in rats

OBJECTIVE: Prolyl oligopeptidase (PREP) has been implicated in neuroinflammatory processes and neuroplasticity and has been suggested as a target for the treatment of neurodegenerative disease. The aim of this investigation was to explore the involvement of PREP in the neuropathologic mechanisms rel...

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Detalles Bibliográficos
Autores principales:	Ali, Idrish, Van Eetveldt, Annemie, Van Elzen, Roos, Kalathil Raju, Tom, Van Der Veken, Pieter, Lambeir, Anne‐Marie, Dedeurwaerdere, Stefanie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Full‐length Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398098/ https://www.ncbi.nlm.nih.gov/pubmed/30868119 http://dx.doi.org/10.1002/epi4.12293

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