Cargando…
Flipping the “switch” on mutant p53 by zinc metallochaperones: how a brief pulse of zinc can reactivate mutant p53 to kill cancer
Autores principales: | Yu, Xin, Carpizo, Darren R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398179/ https://www.ncbi.nlm.nih.gov/pubmed/30847017 http://dx.doi.org/10.18632/oncotarget.26561 |
Ejemplares similares
-
Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics
por: Kogan, Samuel, et al.
Publicado: (2018) -
Small molecule restoration of wildtype structure and function of mutant p53 using a novel zinc-metallochaperone based mechanism
por: Yu, Xin, et al.
Publicado: (2014) -
Zinc shapes the folding landscape of p53 and establishes a pathway for reactivating structurally diverse cancer mutants
por: Blanden, Adam R, et al.
Publicado: (2020) -
p53 and Zinc: A Malleable Relationship
por: Ha, Jeung-Hoi, et al.
Publicado: (2022) -
Therapeutic targeting of BRCA1 and TP53 mutant breast cancer through mutant p53 reactivation
por: Na, Bing, et al.
Publicado: (2019)