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Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis

BACKGROUND: Hepatobiliary tuberculosis is a rare manifestation of Mycobacterium tuberculosis infection, especially in younger patients. The non-specific symptoms and signs as well as the lack of definite imaging characteristics often impedes diagnosis. Definite diagnosis of tuberculosiscan be obtain...

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Autores principales: Pang, Liwei, Wu, Shuodong, Kong, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398219/
https://www.ncbi.nlm.nih.gov/pubmed/30832669
http://dx.doi.org/10.1186/s12879-019-3850-5
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author Pang, Liwei
Wu, Shuodong
Kong, Jing
author_facet Pang, Liwei
Wu, Shuodong
Kong, Jing
author_sort Pang, Liwei
collection PubMed
description BACKGROUND: Hepatobiliary tuberculosis is a rare manifestation of Mycobacterium tuberculosis infection, especially in younger patients. The non-specific symptoms and signs as well as the lack of definite imaging characteristics often impedes diagnosis. Definite diagnosis of tuberculosiscan be obtained through histopathological examination; conventional anti-tuberculosis drugs and surgery are the most commonly recommended treatments. CASE PRESENTATION: A previously healthy 15-year-old rural adolescent male presented with a 2-month history of weight loss and fatigue. We strongly suspected a Klatskin tumor; therefore, exploratory laparotomy was performed. However, the microscopical findings revealed a granuloma consisting of epithelioid cells, caseous necrosis, and lymphocytic infiltration, indicating caseating granulomatous inflammation and yielding a final diagnosis of hepatic hilar tuberculosis. CONCLUSION: Hepatic hilar tuberculosis is an extremely rare case; few physicians may have actually treated a case. This report therefore aims to improve the overall understanding of lymphatic tuberculosis of the hepatic hilum.
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spelling pubmed-63982192019-03-13 Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis Pang, Liwei Wu, Shuodong Kong, Jing BMC Infect Dis Case Report BACKGROUND: Hepatobiliary tuberculosis is a rare manifestation of Mycobacterium tuberculosis infection, especially in younger patients. The non-specific symptoms and signs as well as the lack of definite imaging characteristics often impedes diagnosis. Definite diagnosis of tuberculosiscan be obtained through histopathological examination; conventional anti-tuberculosis drugs and surgery are the most commonly recommended treatments. CASE PRESENTATION: A previously healthy 15-year-old rural adolescent male presented with a 2-month history of weight loss and fatigue. We strongly suspected a Klatskin tumor; therefore, exploratory laparotomy was performed. However, the microscopical findings revealed a granuloma consisting of epithelioid cells, caseous necrosis, and lymphocytic infiltration, indicating caseating granulomatous inflammation and yielding a final diagnosis of hepatic hilar tuberculosis. CONCLUSION: Hepatic hilar tuberculosis is an extremely rare case; few physicians may have actually treated a case. This report therefore aims to improve the overall understanding of lymphatic tuberculosis of the hepatic hilum. BioMed Central 2019-03-04 /pmc/articles/PMC6398219/ /pubmed/30832669 http://dx.doi.org/10.1186/s12879-019-3850-5 Text en © The Author(s). 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Pang, Liwei
Wu, Shuodong
Kong, Jing
Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis
title Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis
title_full Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis
title_fullStr Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis
title_full_unstemmed Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis
title_short Hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis
title_sort hepatic hilar mass in an adolescent: a rare case of hepatobiliary tuberculosis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398219/
https://www.ncbi.nlm.nih.gov/pubmed/30832669
http://dx.doi.org/10.1186/s12879-019-3850-5
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