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Role of hepatocyte nuclear factor 4 alpha in cell proliferation and gemcitabine resistance in pancreatic adenocarcinoma

BACKGROUND: Hepatocyte nuclear factor 4α (HNF4α) is a tissue-specific transcription factor that regulates the expression of numerous genes in hepatocytes and pancreatic β cells. HNF4α has been reported to affect cell proliferation and chemoresistance in several cancers. However, the role of HNF4α in...

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Detalles Bibliográficos
Autores principales:	Sun, Qiqing, Xu, Wenyan, Ji, Shunrong, Qin, Yi, Liu, Wensheng, Hu, Qiangsheng, Zhang, Zheng, Liu, Mengqi, Yu, Xianjun, Xu, Xiaowu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398265/ https://www.ncbi.nlm.nih.gov/pubmed/30867652 http://dx.doi.org/10.1186/s12935-019-0767-4

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