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Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management
Clozapine is an antipsychotic that exhibits superior efficacy and effectiveness for those with schizophrenia and other serious mental illness. However, its side-effect profile and administrative burdens present challenges to its use. In the United States, the medication is grossly underused even tho...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
College of Psychiatric & Neurologic Pharmacists
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398355/ https://www.ncbi.nlm.nih.gov/pubmed/30842912 http://dx.doi.org/10.9740/mhc.2019.03.064 |
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author | Kelly, Deanna L. Love, Raymond C. |
author_facet | Kelly, Deanna L. Love, Raymond C. |
author_sort | Kelly, Deanna L. |
collection | PubMed |
description | Clozapine is an antipsychotic that exhibits superior efficacy and effectiveness for those with schizophrenia and other serious mental illness. However, its side-effect profile and administrative burdens present challenges to its use. In the United States, the medication is grossly underused even though it may improve outcomes and reduce costs. Current barriers to use include lack of prescriber knowledge and confidence, negative prescriber attitudes, special monitoring requirements, administrative factors, lack of clozapine on formularies, lack of support and infrastructure to use the medication within many health systems, and inadequate understanding or acknowledgement of clozapine prescribing and risks by policy makers and payers. Approaches using interprofessional models of care, which include pharmacists specializing in psychiatric care, can help meet the needs of patients receiving clozapine. This article lays out the big picture of barriers to clozapine and how psychiatric pharmacists could play a role in improving access. |
format | Online Article Text |
id | pubmed-6398355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | College of Psychiatric & Neurologic Pharmacists |
record_format | MEDLINE/PubMed |
spelling | pubmed-63983552019-03-06 Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management Kelly, Deanna L. Love, Raymond C. Ment Health Clin Clinical Pearl Clozapine is an antipsychotic that exhibits superior efficacy and effectiveness for those with schizophrenia and other serious mental illness. However, its side-effect profile and administrative burdens present challenges to its use. In the United States, the medication is grossly underused even though it may improve outcomes and reduce costs. Current barriers to use include lack of prescriber knowledge and confidence, negative prescriber attitudes, special monitoring requirements, administrative factors, lack of clozapine on formularies, lack of support and infrastructure to use the medication within many health systems, and inadequate understanding or acknowledgement of clozapine prescribing and risks by policy makers and payers. Approaches using interprofessional models of care, which include pharmacists specializing in psychiatric care, can help meet the needs of patients receiving clozapine. This article lays out the big picture of barriers to clozapine and how psychiatric pharmacists could play a role in improving access. College of Psychiatric & Neurologic Pharmacists 2019-03-01 /pmc/articles/PMC6398355/ /pubmed/30842912 http://dx.doi.org/10.9740/mhc.2019.03.064 Text en © 2019 CPNP. The Mental Health Clinician is a publication of the College of Psychiatric and Neurologic Pharmacists. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Pearl Kelly, Deanna L. Love, Raymond C. Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management |
title | Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management |
title_full | Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management |
title_fullStr | Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management |
title_full_unstemmed | Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management |
title_short | Psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management |
title_sort | psychiatric pharmacist's role in overcoming barriers to clozapine use and improving management |
topic | Clinical Pearl |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398355/ https://www.ncbi.nlm.nih.gov/pubmed/30842912 http://dx.doi.org/10.9740/mhc.2019.03.064 |
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