Functional genomics screen with pooled shRNA library and gene expression profiling with extracts of Azadirachta indica identify potential pathways for therapeutic targets in head and neck squamous cell carcinoma

Tumor suppression by the extracts of Azadirachta indica (neem) works via anti-proliferation, cell cycle arrest, and apoptosis, demonstrated previously using cancer cell lines and live animal models. However, very little is known about the molecular targets and pathways that neem extracts and their a...

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Detalles Bibliográficos
Autores principales: Krishnan, Neeraja M., Katoh, Hiroto, Palve, Vinayak, Pareek, Manisha, Sato, Reiko, Ishikawa, Shumpei, Panda, Binay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2019
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398373/
https://www.ncbi.nlm.nih.gov/pubmed/30842898
http://dx.doi.org/10.7717/peerj.6464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398373/
https://www.ncbi.nlm.nih.gov/pubmed/30842898
http://dx.doi.org/10.7717/peerj.6464

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